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CRLhealthcarenyse

Charles River Laboratories logoCharles River Laboratories

Charles River Laboratories (CRL) is a healthcare company; Yahoo Finance files it under diagnostics & research.

Price

$337.52

+7.83% on Nov 6

Risk

Very High

64.6% vol · 30d

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Key facts, as of

As of November 6, 2026, Charles River Laboratories (CRL) trades at $337.52, up 97.5% over the past year. Its 52-week range runs from $146.20 to $379.63; the price is 11.1% below that high. It is 26.7% below its all-time high of $460.21, reached in September 2021. Over the 10 years to the end of October 2026, with dividends reinvested, it returned +373.7%, against +316.3% for the S&P 500 (SPY). It sits 50.3% above its 200-day average of $224.56, and its 50-day average is above the 200-day too: an uptrend on both averages. Its 30-day volatility is 64.6% annualized, which we rate very high risk. It has a trailing P/E of 366.9.

Cite: Portfolio Terminal, "Charles River Laboratories (CRL) stock analysis", 2026-11-06. https://portfolio-terminal.com/analyse/crl

01Market

Where it trades today

Market cap

$16.17B

Price / earnings

366.9x

Beta

1.34

swings more than the market

Dividend yield

none

Volume

1.06M

avg 1.07M

50-day average

$305.60

200-day average

$224.56

30-day move

+13.3%

52-week range11.1% below the high
low $146.20$337.52high $379.63

trading 82% of the way up its 52-week range

02Price

How the price has moved

30-day price+13.26%
30 days ago$298.00 → $337.52today
1-year performance+101.1%
$202$260$319NovDecJanFebMarAprMayJunJulAugSepOct
CRL · 52 weeks$167.81 → $337.52
03History

How far it is from its record

All-time high

$460.21

Sep 2021, intraday

From the high

−26.7%

+36.4% to regain it

History from

Jun 2000

monthly, Yahoo Finance

10 years

+373.7%

SPY +316.3%

Charles River Laboratories (CRL) is 26.7% below its all-time high of $460.21, reached in September 2021. Over the 10 years to the end of October 2026, with dividends reinvested, it returned +373.7%, against +316.3% for the S&P 500 (SPY).

CRL since Jun 2000−26.7% from the high
$119$239$337.52$460.21 · Sep 202120102020
Month-end closes, split-adjusted · dashed: today
04Read

The read, from its own figures

the read3 sources

What its numbers say

  • CRL closes above its 50-day average ($305.60), and the 50-day sits above the 200-day ($224.56): on both averages the chart reads as an uptrend.
  • At $337.52, CRL is 11.1% below its 1-year high of $379.63, set on October 29, 2026, and 130.9% above its 1-year low of $146.20 (May 19, 2026).
  • Over the past month CRL rose 13.3%, from $298.00 to $337.52.
  • CRL trades at 366.9x its last twelve months of earnings and 26.3x the next twelve months' estimate, so analysts expect earnings 1295.3% higher.
  • Its P/E is 901.2% above the 36.6x median of the 3 other diagnostics & research companies we track (TMO, DHR, A).
  • CRL's 30-day volatility, 64.6% a year, works out to a typical daily move of about 4.1%.
  • Yahoo Finance puts its beta at 1.34: over five years of monthly returns, CRL moved about 1.34% for each 1% move of the S&P 500.

What would change the read

  • A close under the 50-day average, $305.60 (−9.5% from the last close), would turn the read to a pullback; under the 200-day, $224.56 (−33.5%), the longer rise is in question.
  • A close above $379.63 (+12.5%) would be a new 1-year high; below $146.20 (−56.7%), a new 1-year low.

How it is computed

  • Prices are Yahoo Finance's daily candles for CRL, the same ones the chart below draws; the P/E, forward P/E and beta are Yahoo Finance quote fields.
  • The averages are simple means of the last 50 and 200 closes; the 1-year high and low are the highest high and lowest low of the last 252 sessions; the 30-day volatility is the standard deviation of the past month's daily returns, annualized with the square root of 252.
  • Peers are the other companies Yahoo Finance files under diagnostics & research among the assets we track, not a full industry screen; the median counts those with a positive P/E.
  • Every sentence here is written by code from those figures, refreshed daily; nobody edits it for CRL by hand. It describes what the price and the multiples have done, not what they will do, and it is not advice.

Sources

  • Yahoo Finance quote and daily historyopen →

    The candles, the averages' inputs and the quote fields used for CRL. Last refresh: Nov 8, 2026, 10:53 PM UTC.

  • How Portfolio Terminal computes its figuresopen →

    The methodology page behind the analytics and their refresh cadence.

  • Industry classification

    Yahoo Finance's industry, as stored in our list of tracked assets: Diagnostics & Research.

Computed, not written · Code turns the figures above into these sentences; market data refreshed 11/8/2026, 10:53:35 PM. Page built by Julien Esnault. A description of the data, not advice.
05About

What Charles River Laboratories does

profile

Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies. The Discovery and Safety…

Employees

18,300

Industry

Diagnostics & Research

Headquarters

Wilmington, United States

06Analyst Consensus

What analysts expect

CRL carries a buy consensus from 15 analysts, with an average price target of $333.53 versus $337.52 today (-1.2%). Targets are estimates and can move quickly after earnings.

Consensus

Buy

Average target

$333.53

$145.00 to $390.00

Upside to target

-1.2%

Analysts covering

15

Consensus aggregated by Yahoo Finance. Targets are estimates, not forecasts.

07Financial Strength

How the business is doing

CRL generated $3.98B in trailing revenue (-2.2% year over year), with a 1.0% net margin, and $443.24M of free cash flow, against $2.65B of net debt.

Revenue (TTM)

$3.98B

Net margin

1.0%

Revenue growth

-2.2%

Free cash flow

$443.24M

Gross margin

35.1%

Operating margin

23.4%

Return on equity

1.3%

Total cash

$200.38M

Total debt

$2.85B

Earnings growth

523.6%

08Annual Financials

The numbers, year by year

annual financials4 years
Fiscal yearRevenueGross profitOperating incomeNet incomeEPSFree cash flow
2025$4.02B$1.32B$401.14M-$144.34M-$2.91$518.49M
2024$4.05B$1.33B$442.35M$10.30M$0.20$501.61M
2023$4.13B$1.50B$617.26M$474.62M$9.27$365.37M
2022$3.98B$1.46B$650.98M$486.23M$9.57$294.91M
Company filings via Yahoo Finance. Refreshed 11/8/2026.
09Next Earnings

When it reports next

Next report

Nov 4, 2026

EPS estimate

$3.31

Revenue estimate

$973.25M

Estimates aggregated by Yahoo Finance. Dates move and estimates change until the report lands.

10ETFs

Which ETFs hold it

CRL is in 11 of the 54 ETFs we track. It weighs most in XLV: 0.22% of the fund, holding #51 of 62.

etfs holding it11 of 54 funds
XLV0.22%#51 of 62RSP0.22%#82 of 504VB0.18%#115 of 1,301SPY0.02%#432 of 504IVV0.02%#433 of 503CSPX0.02%#433 of 503VUAA0.02%#430 of 503VOO0.02%#430 of 505ITOT0.02%#510 of 2,423VTI0.02%#515 of 3,516VT0.01%#1089 of 10,155
11Industry

How its figures compare with those peers

versus its peersCRL vs the median of TMO, DHR, A
metricCRLmedian · ngap
price / earnings366.9x36.6x · 3+901%
beta1.340.84 · 3+58%
dividend yield0.00%0.58% · 3−100%
30-day volatility64.6%28.9% · 3+123%
Live Yahoo Finance figures for each name; n counts the peers that have the figure.
12Peers

Companies in the same industry

CRL beside the other companies Yahoo Finance files under diagnostics & research among the assets we track (TMO, DHR, A, largest first).

peers4 companies
companypricemarket cap
Charles River Laboratories logoCRL$337.52$16.17B
Thermo Fisher Scientific logoTMO$694.76$257.42BDHDHR$230.25$161.99BAgilent Technologies logoA$174.76$49.28B
Any row opens that company's own analysis.
13Technicals

What the chart is saying

In an uptrend, above both moving averages.

uptrend
crl · daily
50-day 306200-day 225resistancesupport
1502003007030RSI 14 · 54volS 239S 229338JunJulAugSepOctNov
Daily candles · CRLLevels are zones where the price turned at least twice in the last year. Last close $337.52 on 2026-11-06.

RSI (14)

54

neutral zone

vs 50-day

+10.4%

avg $305.60

vs 200-day

+50.3%

avg $224.56

From 1-year high

−11.1%

high $379.63 · 2026-10-29

levels and the read65% annualized vol · 30d
support$239.07turned here 3×−29.2%
support$228.64turned here 2×−32.3%
  • Price is 10.4% above its 50-day average and 50.3% above its 200-day.
  • The 50-day crossed above the 200-day on 2026-07-06 (a “golden cross”).
  • RSI at 54 is neither stretched nor washed out.
  • Nothing above has stopped it this year; the nearest floor is $239.07 (-29.2%).

A description of the chart, not advice. Indicators describe what the price has done; none of them knows what it does next.

14Questions

Questions people ask about it

questions8 answered

How is CRL valued right now?

Charles River Laboratories trades at 366.9 times its last twelve months of earnings and 26.3 times the next twelve months' estimate (Yahoo Finance, November 6, 2026). On the chart: in an uptrend, above both moving averages. Price is 10.4% above its 50-day average and 50.3% above its 200-day.

What is the risk level of CRL?

Based on 30-day volatility of 64.6%, CRL has VERY HIGH risk. Its beta of 1.34 means it has swung more than the S&P 500 over the last five years.

Does CRL pay dividends?

Yahoo Finance shows no dividend yield for Charles River Laboratories (November 6, 2026).

How far is CRL from its all-time high?

Charles River Laboratories is 26.7% below its all-time high of $460.21, reached in September 2021. Over the 10 years to the end of October 2026, with dividends reinvested, it returned +373.7%, against +316.3% for the S&P 500 (SPY).

Which ETFs hold CRL?

11 of the 54 popular ETFs we track hold Charles River Laboratories. The largest weights: XLV (0.22%), RSP (0.22%), VB (0.18%), SPY (0.02%) and IVV (0.02%). Measured on each issuer's full holdings file, dated September 30 to October 18, 2026.

How much of VOO is CRL?

0.02%, as of September 30, 2026: CRL is holding #430 of 505 in Vanguard's file for VOO. $1,000 in VOO puts about $0.21 in Charles River Laboratories.

What is the analyst price target for CRL?

The average analyst price target for Charles River Laboratories (CRL) is $333.53 based on 15 analyst estimates, about 1.2% below the current price of $337.52. The published range runs from $145.00 to $390.00.

How much revenue does CRL generate?

Charles River Laboratories reported $3.98B in trailing twelve-month revenue. Revenue growth is running at -2.2% year over year. Net margin sits at 1.0%. Figures are aggregated from company filings by Yahoo Finance and refresh on an hourly cadence.

Compare CRL with anything

Five years side by side: what $10,000 became, how far each fell, whether they move together.

Charles River Laboratories logo